TRPC2

Pseudogene in the species Homo sapiens
TRPC2
Identifiers
AliasesTRPC2, transient receptor potential cation channel subfamily C member 2, pseudogene, transient receptor potential cation channel subfamily C member 2 (pseudogene)
External IDsGeneCards: TRPC2
Gene location (Human)
Chromosome 11 (human)
Chr.Chromosome 11 (human)[1]
Chromosome 11 (human)
Genomic location for TRPC2
Genomic location for TRPC2
Band11p15.4Start3,616,679 bp[1]
End3,637,672 bp[1]
Orthologs
SpeciesHumanMouse
Entrez

7221

n/a

Ensembl

ENSG00000182048

n/a

UniProt

n
a

n/a

RefSeq (mRNA)

n/a

n/a

RefSeq (protein)

n/a

n/a

Location (UCSC)Chr 11: 3.62 – 3.64 Mbn/a
PubMed search[2]n/a
Wikidata
View/Edit Human

Transient receptor potential cation channel, subfamily C, member 2, also known as TRPC2, is a protein that in humans is encoded by the TRPC2 pseudogene. This protein is not expressed in humans but is in certain other species such as mouse.[3]

Interactions

TRPC2 has been shown to interact with TRPC6.[4]

See also

  • TRPC

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000182048 – Ensembl, May 2017
  2. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ^ Clapham DE, Julius D, Montell C, Schultz G (December 2005). "International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels". Pharmacol. Rev. 57 (4): 427–50. doi:10.1124/pr.57.4.6. PMID 16382100. S2CID 17936350.
  4. ^ Chu, Xin; Tong Qin; Cheung Joseph Y; Wozney Jocelyn; Conrad Kathleen; Mazack Virginia; Zhang Wenyi; Stahl Richard; Barber Dwayne L; Miller Barbara A (Mar 2004). "Interaction of TRPC2 and TRPC6 in erythropoietin modulation of calcium influx". J. Biol. Chem. 279 (11). United States: 10514–22. doi:10.1074/jbc.M308478200. ISSN 0021-9258. PMID 14699131.

Further reading

  • Islam, Md. Shahidul (January 2011). Transient Receptor Potential Channels. Advances in Experimental Medicine and Biology. Vol. 704. Berlin: Springer. p. 700. ISBN 978-94-007-0264-6.
  • Clapham DE, Julius D, Montell C, Schultz G (2006). "International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels". Pharmacol. Rev. 57 (4): 427–50. doi:10.1124/pr.57.4.6. PMID 16382100. S2CID 17936350.
  • Yildirim E, Birnbaumer L (2007). TRPC2: Molecular Biology and Functional Importance. Handbook of Experimental Pharmacology. Vol. 179. pp. 53–75. doi:10.1007/978-3-540-34891-7_3. ISBN 978-3-540-34889-4. PMID 17217050.

External links

  • TRPC2+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

  • v
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Ligand-gated
Voltage-gated
Constitutively active
Proton-gated
Voltage-gated
Calcium-activated
Inward-rectifier
Tandem pore domain
Voltage-gated
Miscellaneous
Cl−: Chloride channel
H+: Proton channel
M+: CNG cation channel
M+: TRP cation channel
H2O (+ solutes): Porin
Cytoplasm: Gap junction
By gating mechanism
Ion channel class
see also disorders
  • v
  • t
  • e
TRP channel modulators
TRPA
Activators
Blockers
TRPC
Activators
Blockers
TRPM
Activators
Blockers
TRPML
Activators
Blockers
TRPP
Activators
Blockers
TRPV
Activators
Blockers
See also: Receptor/signaling modulators • Ion channel modulators


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