GPR174

Protein-coding gene in humans
GPR174
Identifiers
AliasesGPR174, GPCR17, LYPSR3, FKSG79, G protein-coupled receptor 174
External IDsOMIM: 300903 MGI: 2685222 HomoloGene: 13059 GeneCards: GPR174
Gene location (Human)
X chromosome (human)
Chr.X chromosome (human)[1]
X chromosome (human)
Genomic location for GPR174
Genomic location for GPR174
BandXq21.1Start79,144,688 bp[1]
End79,175,318 bp[1]
Gene location (Mouse)
X chromosome (mouse)
Chr.X chromosome (mouse)[2]
X chromosome (mouse)
Genomic location for GPR174
Genomic location for GPR174
BandX|X DStart106,299,484 bp[2]
End106,340,375 bp[2]
RNA expression pattern
Bgee
HumanMouse (ortholog)
Top expressed in
  • thymus

  • lymph node

  • appendix

  • spleen

  • superficial temporal artery

  • blood

  • bone marrow cells

  • thymus

  • jejunal mucosa

  • rectum
Top expressed in
  • spleen

  • blood

  • thymus

  • subcutaneous adipose tissue

  • white adipose tissue

  • dermis

  • mammary gland

  • oocyte

  • jejunum

  • upper arm
More reference expression data
BioGPS
More reference expression data
Gene ontology
Molecular function
  • G protein-coupled receptor activity
  • signal transducer activity
  • bioactive lipid receptor activity
Cellular component
  • integral component of membrane
  • plasma membrane
  • membrane
  • integral component of plasma membrane
Biological process
  • signal transduction
  • G protein-coupled receptor signaling pathway
  • positive regulation of Rho protein signal transduction
  • T cell homeostasis
  • positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G protein-coupled signaling pathway
Sources:Amigo / QuickGO
Orthologs
SpeciesHumanMouse
Entrez

84636

213439

Ensembl

ENSG00000147138

ENSMUSG00000073008

UniProt

Q9BXC1

Q3U507

RefSeq (mRNA)

NM_032553

NM_001033251
NM_001177781
NM_001177782
NM_001358747

RefSeq (protein)

NP_115942

NP_001028423
NP_001171252
NP_001171253
NP_001345676

Location (UCSC)Chr X: 79.14 – 79.18 MbChr X: 106.3 – 106.34 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Probable G-protein coupled receptor 174 is a protein that in humans is encoded by the GPR174 gene.[5]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000147138 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000073008 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ "Entrez Gene: GPR174 G protein-coupled receptor 174".

Further reading

  • Takeda S, Kadowaki S, Haga T, et al. (2002). "Identification of G protein-coupled receptor genes from the human genome sequence". FEBS Lett. 520 (1–3): 97–101. doi:10.1016/S0014-5793(02)02775-8. PMID 12044878. S2CID 7116392.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Ross MT, Grafham DV, Coffey AJ, et al. (2005). "The DNA sequence of the human X chromosome". Nature. 434 (7031): 325–37. Bibcode:2005Natur.434..325R. doi:10.1038/nature03440. PMC 2665286. PMID 15772651.
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Neurotransmitter
Adrenergic
Purinergic
Serotonin
Other
Metabolites and
signaling molecules
Eicosanoid
Other
Peptide
Neuropeptide
Other
Miscellaneous
Taste, bitter
Orphan
Other
Adhesion
Orphan
Other
Taste, sweet
Other
Class F: Frizzled & Smoothened
Frizzled
Smoothened